Hyperpositive nonlinear effects in asymmetric catalysis
نویسندگان
چکیده
منابع مشابه
Expansion of the Concept of Nonlinear Effects in Catalytic Reactions Beyond Asymmetric Catalysis.
The observation and investigation of nonlinear effects in catalytic reactions provides valuable mechanistic insight. However, the applicability of this method was, until now, limited to molecules possessing chirality and therefore to asymmetric synthesis. The concept of nonlinear effects is expanded to catalytic reactions beyond asymmetric catalysis by using derivatives instead of enantiomers a...
متن کاملAsymmetric Catalysis.
H ighlighting this issue of PNAS and the forthcoming one* is a Special Feature comprising 8 Perspectives and 44 research articles that cover aspects of asymmetric catalysis, the phenomenon whereby a chiral catalyst promotes the conversion of an achiral substrate to a chiral product with a preference for the formation of one of the mirror image isomers (enantiomers). The demand for chiral compou...
متن کاملStrategies in asymmetric catalysis
The stereochemistry of an organic compound can have a profound influence on many of its most important properties. For example, the enantiomeric forms of a drug molecule can have completely different biological effects, and polymers that differ only in the stereochemistry of their backbones can have quite dissimilar macroscopic physical characteristics. Control over the stereochemical outcome o...
متن کاملNon-linear Effects in Asymmetric Catalysis: Whys and Wherefores
It is argued that the titled non-linear effects (NLE) may arise whenever the order of the reaction in the chiral catalyst in greater than 1. In a fundamental departure from previous approaches, this is mathematically elaborated for the second order case. (NLE may also be observed if the chiral catalyst forms non-reacting dimers in a competing equilibrium; practically, however, this implies the ...
متن کاملSequential column asymmetric catalysis.
Since the introduction of catalysts and reagents on solid-support, researchers have developed new reaction systems to take advantage of their insoluble nature by designing multistep reaction sequences, high-throughput purification techniques, and combinatorial synthesis methods. The continuous flow system is one of these advancements and represents the foundation of a new technique termed seque...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Catalysis
سال: 2020
ISSN: 2520-1158
DOI: 10.1038/s41929-020-0441-1